The Nigeria international took his tally to five goals in 15 league games this campaign, same amount he managed for the enitre 2016-17 season.
Senegal’s Mamadou Sylla ran through the Essevee’s defence to set up Simon for a cool finish in the 29th minute.
The hosts, who had lost their six previous games across all competitions, struggled to get an equaliser as the 22-year-old’s first half effort stood as the only difference.
Late on, compatroit Anderson Esiti was given his marching orders after receiving a second yellow card.
Yves Vanderhaeghe’s men sealed their seventh win in the league this season and climbed to the fifth spot in the Belgian top-flight table with 25 points from 17 games.
The Ghelamco Arena outfit welcome Kortrijk for their next Belgian top division outing on Saturday.
